Sla links over
  • Spring naar de inhoud
  • Spring naar het menu
Inloggen
logo
  • About DCS
    • Agenda
    • Board
    • ALV-2022-2023
    • ALV-2021
    • ALV-2020
  • Activities
    • Catalysis Workshop
    • NCCC
    • Travel Grant
    • Netherlands Catalysis and Chemistry Award
    • DCS Award
    • N3C Award
    • DCS Mentoring program
  • News
  • DZA
    • About DZA
    • DZA Board
  • Membership
  • About DCS
    • Agenda
    • Board
    • ALV-2022-2023
    • ALV-2021
    • ALV-2020
  • Activities
    • Catalysis Workshop
    • NCCC
    • Travel Grant
    • Netherlands Catalysis and Chemistry Award
    • DCS Award
      • DCS Thesis Award
      • Former Recipients DCS Award
    • N3C Award
    • DCS Mentoring program
  • News
  • DZA
    • About DZA
    • DZA Board
  • Membership
Inloggen

Hermen Overkleeft RSC Jeremy Knowles Award 2015 Winner

Hermen-Overkleeft.jpgmaandag 14 september 2015

Awarded for his innovative and insightful development of activity-based protein probes for the imaging and identification of enzymes in health and disease.

About the Winner

Herman Overkleeft obtained his PhD degree in 1997 under the guidance of Professor Upendra Pandit (University of Amsterdam) on the subject of iminosugars as glycosidase inhibitors. He then did post-doctoral research with Professor Jacques van Boom (Leiden University, the Netherlands, 1997-1999) on ring-closing metathesis in the synthesis of polyhydroxylated oxacycles and azacycles, and with Professor Hidde Ploegh (Harvard Medical School, Boston, CA, USA, 1999-2001) on inhibition of proteases involved in human adaptive immunity. He returned to the Netherlands in 2001 to assume his current chair of bioorganic chemistry at Leiden University.

His current research focuses on enzyme inhibitors and activity-based probes in chemical biology and medicinal chemistry, in particular in glycobiology and immunology. Comparative activity-based protein profiling experiments are used to study cysteine proteases, proteasomes and retaining glycosidases. Competitive activity-based protein profiling has yielded selective inhibitors for five of the six catalytic activities of human constitutive proteasomes and immunoproteasomes. Activity-based probes are equipped with any of a number of fluorophores, cell surface receptor targeting moieties or with bioorthogonal tags for instalment of these by bioorthogonal chemistry.

Herman Overkleeft has a long-standing collaboration with Professor Hans Aerts (formerly University of Amsterdam, now Leiden University) on glycolipid metabolism and lysosomal storage disorders. Competitive inhibitors selective for glucosylceramidase, acid glucosylceramidase and neutral glucosylceramidase has been developed, and current focus is on the development of a dual glucosylceramide synthase/neutral glucosylceramidase inhibitor as a potential lead for clinical development towards Gaucher disease and neuropathological disorders.

Bron: RSC

« Terug

Reacties op 'Hermen Overkleeft RSC Jeremy Knowles Award 2015 Winner'

  • Vorige pagina
  • 1
  • ...
  • 3
  • 4
  • 5
  • ...
  • 8
  • Volgende pagina
  1. Swarna Yadav 16-08-2024 14:28
    Lajpat Nagar Independent escorts enjoy their own kinky desires of sex and get relaxed from their stress of job with their client to whom they deliver happiness and satisfaction. If you wish to meet truly independent kind of Lajpat Nagar Escort then just contact us now and meet with your dream independent female escorts in Lajpat Nagar at.

    Reply

  2. briansclub.cm 28-08-2024 15:08
    Briansclub Dumps and CVV2 Shop. The best quality cards from the Legendary Brian Krebs at Briansclub cm & <a href="https://brriansclub.to/">briansclub.cm</a>.

    Reply

  3. shkokkaescort 02-09-2024 06:52
    Whether you're looking for <a href="https://shkokka.com/">hot call girls in Gurgaon</a> or a more exclusive call girl service in Gurgaon, the city has plenty to offer. By choosing independent female escorts, you ensure a personalized and memorable experience. Take your time to explore your options and ensure a safe and enjoyable time in Gurgaon.

    Reply

  4. shkokkaescort 02-09-2024 06:54
    The bustling city of Gurgaon is known for its vibrant nightlife and plethora of entertainment options. Among these, call girl service in Gurgaon play a significant and often sought-after role. With an increasing demand for companionship and entertainment, these services have evolved to offer discreet and professional experiences for clients.

    Reply

  5. aliacacia 05-09-2024 11:11
    The <a href="https://connectionsnytunlimited.io">Connections</a> often requires recalling definitions or meanings of words that may not be in your immediate vocabulary, improving memory recall and retention.

    Reply

  6. aliacacia 05-09-2024 11:14
    [Connections](https://connectionsnytunlimited.io) is a standout game for word puzzle fans, offering endless puzzles that challenge the mind in new and exciting ways.

    Reply

  7. Ruby Rajput 17-09-2024 15:31
    For anyone who wishes to go out and have fun with an attractive lady, there are various options available, ranging from the classy ladies to the cheap ones. Independent <a href="https://www.jennyaroraescort.com/chhatarpur-call-girls.html"> Escort Chhatarpur </a> are available to meet men, with options from chancing upon a friend for the night to a passionate sexual partner.

    Reply

  8. Ruby Rajput 17-09-2024 15:32
    Chhatarpur Escort service can be described as the arrangement in which a gentleman hires the company of an attractive and intelligent girl for a particular period for a certain fee. While the services of escorts may vary, these ladies often offer their company for social functions, dinner dates, and even parties. However, other Escort Chhatarpur offer other facilities that may include role play, sensual massages and other adult activities.

    Reply

  9. Miss Shweta 26-09-2024 14:10
    The best Aerocity escort service, with a huge selection of escort girls, is missshweta. You can contact us by phone or email to book an appointment if you're searching for the greatest escort services. Although our phone number and email address are given on the website

    Reply

  10. Miss Shweta 26-09-2024 14:11
    <p><span data-sheets-root="1"><br /><span data-sheets-root="1">The best <a href="https://www.missshweta.in/aerocity-escorts/"><strong>Aerocity escort service</strong></a>, with a huge selection of escort girls, is missshweta. You can contact us by phone or email to book an appointment if you're searching for the greatest escort services. Although our phone number and email address are given on the website</span></span></p>

    Reply

  11. Miss Shweta 26-09-2024 14:11
    The best Aerocity escort service, with a huge selection of escort girls, is missshweta. You can contact us by phone or email to book an appointment if you're searching for the greatest escort services. Although our phone number and email address are given on the website

    Reply

  12. Lust Delhi 26-09-2024 14:13
    Lustdelhi.com is the best escort agency with a large collection of escort girls. If you're looking for the best delhi escort services, you can make an appointment with Lustdelhi's Escorts via our email ID or number. The address and email ID are available on the website, but before you contact us, please go through our terms and conditions

    Reply

  13. girlsclub 19-10-2024 09:05
    https://girlsclub.in/
    https://girlsclub.in/about.html
    https://girlsclub.in/gallery.html
    https://girlsclub.in/fees.html
    https://girlsclub.in/call-girl-five-star.html
    https://girlsclub.in/contact.html
    https://girlsclub.in/call-girl-aerocity.html
    https://girlsclub.in/call-girl-in-delhi.html
    https://girlsclub.in/call-girl-mahipalpur.html
    https://girlsclub.in/call-girl-dwarka.html
    https://girlsclub.in/call-girl-nehru-place.html
    https://girlsclub.in/call-girl-chhatarpur.html
    https://girlsclub.in/call-girl-saket.html
    https://girlsclub.in/cal...rl-connaught-place.html
    https://girlsclub.in/call-girl-mayurvihar.html
    https://girlsclub.in/call-girl-noida.html
    https://girlsclub.in/noi...all-girl-gaur-city.html
    https://girlsclub.in/call-girl-greater-noida.html
    https://girlsclub.in/call-girl-ghaziabad.html
    https://girlsclub.in/call-girls-indirapuram.html
    https://girlsclub.in/call-girls-vaishali.html
    https://girlsclub.in/cal...-royal-plaza-hotel.html
    https://girlsclub.in/cal...rl-the-grand-hotel.html
    https://girlsclub.in/call-girl-pride-plaza.html
    https://girlsclub.in/cal...l-novotel-aerocity.html
    https://girlsclub.in/cal...crossings-republik.html
    https://girlsclub.in/raipur-escorts.html
    https://girlsclub.in/call-girl-goa.html
    https://girlsclub.in/red-light-areas-in-delhi.html
    https://girlsclub.in/dehati-sexy-video-list.html
    https://girlsclub.in/indian-female-pornstars.html
    https://girlsclub.in/tam...ex-whatsapp-groups.html
    https://girlsclub.in/call-girls-near-me.html
    https://girlsclub.in/marathi-sexy-video.html
    https://girlsclub.in/gujarati-sexy-video-list.html
    https://girlsclub.in/call-girl-rohini.html
    https://girlsclub.in/call-girl-lucknow.html
    https://girlsclub.in/call-girl-panaji.html
    https://girlsclub.in/hyd...ndependent-service.html
    https://girlsclub.in/call-girl-gurgaon.html
    https://girlsclub.in/jaipur-escorts-service.html
    https://girlsclub.in/kerala-call-girls.html
    https://girlsclub.in/bangalore-call-girls.html
    https://girlsclub.in/call-girls-chandigarh.html
    https://girlsclub.in/call-girl-zirakpur.html
    https://girlsclub.in/call-girl-mohali.html
    https://girlsclub.in/call-girl-mumbai.html
    https://girlsclub.in/call-girl-kolkata.html
    https://girlsclub.in/call-girl-ludhiana.html
    https://girlsclub.in/call-girl-amritsar.html
    https://girlsclub.in/call-girl-jalandhar.html
    https://girlsclub.in/udaipur-escort-service.html
    https://girlsclub.in/pune-escort-service.html
    https://girlsclub.in/noi...cort-girls-contact.html
    https://girlsclub.in/gur...cort-girls-contact.html
    https://girlsclub.in/goa...rt-contact-numbers.html
    https://girlsclub.in/ban...cort-girls-contact.html
    https://girlsclub.in/escort-contact-number.html
    https://girlsclub.in/uda...rt-contact-numbers.html
    https://girlsclub.in/red...areas-in-hyderabad.html
    https://girlsclub.in/bhojpuri-sexy-video-list.html
    https://girlsclub.in/marwadi-sexy-video-list.html
    https://girlsclub.in/american-sexy-videos.html
    https://girlsclub.in/hindi-sexy-video-list.html
    https://callgirlsinzirakpur.in/
    https://www.anchalkapoor.com/
    https://www.honeytyagi.com/
    https://www.zoya.club/
    https://www.mohalicallgirls.com/
    https://callgirls4you.com/
    https://www.mohalicallgirlsagency.in/
    https://www.sarakaur.in/
    https://www.honeytyagi.com/bangalore-escorts/
    https://www.navleenkaur.com/
    https://www.preetkaur.com/
    https://www.ayeshakaur.com
    https://www.zoya.club/jaipur-call-girls.php

    Reply

  14. Escorts Service In Lahore 21-10-2024 18:02
    Consequently, many agencies adhere strictly to ethical practices aimed at ensuring the safety and well-being of both escorts and clients, establishing a professional yet intimate atmosphere that fosters genuine connections.
    <a href="https://callgirlsescortinlahore.com/">Escorts In Lahore</a>

    Reply

  15. Bangalore escorts 29-10-2024 07:19
    https://www.topbangaloreescortservice.com
    https://www.topbangalore...re-escort-services.html
    https://www.topbangalore...rvice-in-bangalore.html
    https://www.topbangalore...ore-escort-service.html
    https://www.topbangalore...rvice-in-bangalore.html
    https://www.topbangalore...orts-service-about.html
    https://www.topbangalore...-bangalore-gallery.html
    https://www.topbangalore...lore-phone-numbers.html
    https://www.topbangalore...girls-in-bangalore.html
    https://www.topbangalore...del-escort-service.html
    https://www.topbangalore...ewife-in-bangalore.html
    https://www.topbangalore...ore-escort-service.html
    https://www.topbangalore...scort-in-bangalore.html
    https://www.topbangalore...girls-in-bangalore.html
    https://www.topbangalore...ss-escort-services.html
    https://www.topbangalore...girls-in-bangalore.html
    https://www.topbangalore...vices-in-bangalore.html
    https://www.topbangalore...vices-in-bangalore.html
    https://www.topbangalore...vices-in-bangalore.html
    https://www.topbangalore...vices-in-bangalore.html
    https://www.topbangalore...vices-in-bangalore.html
    https://www.topbangalore...vices-in-bangalore.html
    https://www.topbangalore...vices-in-bangalore.html
    https://www.topbangalore...vices-in-bangalore.html
    https://www.skkoker.com
    https://www.skkoker.com/bangalore-escorts.html

    Reply

  16. Masticlubs 30-10-2024 13:20
    Hi,
    I enjoyed your write-up. It gives the substantial amount of information that I was looking for. I am an aspiring blogger and want to get a new one for me. I would really appreciate if you also guide me through the process of creating a blog.
    Thank you in advance.
    https://in.masticlubs.com/call-girls/surat/
    https://in.masticlubs.com/call-girls/vadodara/
    https://in.masticlubs.com/call-girls/nashik/
    https://in.masticlubs.com/call-girls/bhopal/
    https://in.masticlubs.com/call-girls/rajkot/
    https://in.masticlubs.com/call-girls/lucknow/
    https://in.masticlubs.com/call-girls/ranchi/
    https://in.masticlubs.com/call-girls/patna/
    https://in.masticlubs.com/call-girls/vapi/
    https://in.masticlubs.com/call-girls/amritsar/
    https://in.masticlubs.com/call-girls/indore/
    https://in.masticlubs.com/call-girls/thane/
    https://in.masticlubs.com/call-girls/madurai/
    https://in.masticlubs.co...ll-girls/visakhapatnam/

    Reply

  17. Avni 03-11-2024 11:53
    https://www.avnidutta.com/
    https://www.kolkatarussian.com
    https://www.avnidutta.co...ta-russian-escorts.html
    https://www.avnidutta.com/kolkata-call-girls.html
    https://www.avnidutta.com/newtown-escorts.html
    https://www.avnidutta.com/salt-lake-escorts.html
    https://www.avnidutta.com/park-street-escorts.html
    https://www.avnidutta.co...kata-hotel-escorts.html
    https://www.avnidutta.co...-housewife-escorts.html

    Reply

  18. Avni 03-11-2024 11:53
    https://www.avnidutta.com/siliguri-escorts.html
    https://www.avnidutta.co...ience-city-escorts.html
    https://www.avnidutta.com/dharmatala-escorts.html
    https://www.avnidutta.com/airport-escorts.html
    https://www.avnidutta.com/ballygunge-escorts.html
    https://www.avnidutta.com/jadavpur-escorts.html
    https://www.avnidutta.com/em-bypass-escorts.html
    https://www.avnidutta.co...ic-village-escorts.html
    https://www.avnidutta.com/shapoorji-escorts.html
    https://www.avnidutta.com/baruipur-escorts.html
    https://www.avnidutta.com/tagore-park-escorts.html
    https://www.avnidutta.com/baguiati-escorts.html
    https://www.avnidutta.com/belghoria-escorts.html
    https://www.avnidutta.com/ultadanga-escorts.html
    https://www.avnidutta.com/ruby-escorts.html
    https://www.avnidutta.com/sealdah-escorts.html
    https://www.avnidutta.com/darjeeling-escorts.html
    https://www.avnidutta.com/belgachia-escorts.html
    https://www.avnidutta.co...dhan-nagar-escorts.html
    https://www.avnidutta.com/chetla-escorts.html
    https://www.avnidutta.com/chinar-park-escorts.html
    https://www.avnidutta.com/dum-dum-escorts.html
    https://www.avnidutta.com/kalyani-escorts.html
    https://www.avnidutta.com/alipore-escorts.html
    https://www.avnidutta.com/rajarhat-escorts.html
    https://www.avnidutta.com/sonagachi-escorts.html
    https://www.avnidutta.com/beliaghata-escorts.html
    https://www.avnidutta.com/bara-bazar-escorts.html
    https://www.avnidutta.com/outcall-escorts.html
    https://www.avnidutta.com/incall-escorts.html
    https://www.avnidutta.com/asansol-escorts.html
    https://www.avnidutta.com/durgapur-escorts.html
    https://www.avnidutta.com/bansdroni-escorts.html
    https://www.avnidutta.com/barrackpore-escorts.html
    https://www.avnidutta.com/behala-escorts.html
    https://www.avnidutta.com/lake-town-escorts.html
    https://www.avnidutta.com/budge-budge-escorts.html

    Reply

  19. Night Life 04-11-2024 11:07
    We are a 24/7 Modelling Agency we work 24/7 from 11 am to 4 pm. Our company offers clients looking for an adult service provider with girls at affordable prices. We hold meetings at a time convenient for us and a location chosen by our clients. We always provide excellent cost performance. <a href="https://www.nightlife4u.com/">kolkata escorts</a> ||

    Reply

  20. Night Life 04-11-2024 11:08
    https://www.nightlife4u.com
    https://www.nightlife4u.com/russian-escorts.html
    https://www.nightlife4u....ark-street-escorts.html
    https://www.nightlife4u.com/salt-lake-escorts.html
    https://www.nightlife4u.com/newtown-escorts.html
    https://www.nightlife4u....dharmatala-escorts.html
    https://www.nightlife4u.com/airport-escorts.html
    https://www.nightlife4u....ballygunge-escorts.html
    https://www.nightlife4u.com/jadavpur-escorts.html
    https://www.nightlife4u.com/em-bypass-escorts.html
    https://www.nightlife4u....ic-village-escorts.html
    https://www.nightlife4u.com/lake-town-escorts.html
    https://www.nightlife4u....udge-budge-escorts.html
    https://www.nightlife4u....ir-hostess-escorts.html
    https://www.nightlife4u.com/housewife-escorts.html
    https://www.nightlife4u.com/hotel-escorts.html
    https://www.nightlife4u.com/shapoorji-escorts.html
    https://www.nightlife4u.com/asansol-escorts.html
    https://www.nightlife4u.com/ruby-escorts.html
    https://www.nightlife4u.com/sealdah-escorts.html
    https://www.nightlife4u....darjeeling-escorts.html
    https://www.nightlife4u.com/belgachia-escorts.html
    https://www.nightlife4u....dhan-nagar-escorts.html
    https://www.nightlife4u.com/chetla-escorts.html
    https://www.nightlife4u....hinar-park-escorts.html
    https://www.nightlife4u.com/dum-dum-escorts.html
    https://www.nightlife4u.com/siliguri-escorts.html
    https://www.nightlife4u.com/kalyani-escorts.html
    https://www.nightlife4u.com/alipore-escorts.html
    https://www.nightlife4u.com/rajarhat-escorts.html
    https://www.nightlife4u.com/sonagachi-escorts.html
    https://www.nightlife4u....ience-city-escorts.html
    https://www.nightlife4u.com/baruipur-escorts.html
    https://www.nightlife4u....agore-park-escorts.html
    https://www.nightlife4u.com/baguiati-escorts.html
    https://www.nightlife4u.com/belgharia-escorts.html
    https://www.nightlife4u.com/ultadanga-escorts.html
    https://www.nightlife4u....beliaghata-escorts.html
    https://www.nightlife4u....bara-bazar-escorts.html
    https://www.nightlife4u.com/durgapur-escorts.html
    https://www.nightlife4u.com/bansdroni-escorts.html
    https://www.nightlife4u....arrackpore-escorts.html
    https://www.nightlife4u.com/behala-escorts.html

    Reply

  21. Night Life 04-11-2024 11:10
    <a href="https://www.nightlife4u.com/">kolkata escorts</a>

    Reply

  22. indufun 16-11-2024 08:32
    indufun.com is a free adult classified ad portal that allow the publishers to promote their adult services. The ad portal is not supposed to intervene in any kind of relationship or settlement between the pleasure seekers and service providers.
    https://indufun.com/

    Reply

  23. sonu 16-11-2024 08:35
    Darling men out there! My name is Neetu. I am your seductive delight in noida! I embody passion and excitement, offering you an unforgettable night of pleasure. As a sexy model, I specialise in a range of sensual experiences designed to fulfil your deepest desires. I excel in various intimate acts, from the enticing O-Level and COB to the adventurous A-Level and 69 positions. My expertise extends to erotic massages, golden showers, and catering to couples. With my GFE (Girlfriend Experience), I create a genuine connection, making our time together truly special.
    https://cg.naughtygal.in/noida-call-girls.html
    https://cg.naughtygal.in/gurgaon-call-girls.html
    https://cg.naughtygal.in...all-girls-in-delhi.html
    https://indufun.com/

    Reply

  24. Kolkata Call Girls 21-11-2024 09:16
    Kolkata, the place of love for all. Visit us any time and call for sexy call girls.

    <a href="https://www.kolkatanights.in/call-girls/kolkata/">Kolkata call girl Services</a> \\ <a href="https://www.kolkatanights.in/call-girls/kolkata/">kolkata call girl sex</a> || <a href="https://www.kolkatanights.in/call-girls/kolkata/">call girls in kolkata</a> || <a href="https://www.kolkatanights.in/call-girls/kolkata/">call girl services kolkata</a>

    <a href="https://www.kolkatanights.in/kolkata-escort/">escort service in kolkata</a>
    <a href="https://www.kolkatanights.in/kolkata-escort/">escorts service in kolkata</a>
    <a href="https://www.kolkatanights.in/kolkata-escort/">kolkata escort service</a>
    <a href="https://www.kolkatanights.in/kolkata-escort/">female escorts in kolkata</a>
    <a href="https://www.kolkatanights.in/kolkata-escort/">vip escorts kolkata</a>
    <a href="https://www.kolkatanights.in/kolkata-escort/">escort services kolkata</a>

    <a href="https://www.kolkatanights.in/call-girls/asian/">asian escort services in Kolkata</a>
    <a href="https://www.kolkatanights.in/call-girls/asian/">asian call girl services in Kolkata</a>
    <a href="https://www.kolkatanights.in/kolkata-airhostess-call-girls/">air hostess escort in Kolkata</a>
    <a href="https://www.kolkatanights.in/kolkata-airhostess-call-girls/">air hostess call girl in Kolkata</a>
    <a href="https://www.kolkatanights.in/call-girls/russian/">Russian call girls kolkata</a>
    <a href="https://www.kolkatanights.in/dum-dum-escort/">dum dum escort service</a>

    Call Now or WhatsApps us.

    Reply

  25. Avni 22-11-2024 11:15
    <a href="https://www.avnidutta.com">sex life in kolkata</a>||

    Reply

  • Vorige pagina
  • 1
  • ...
  • 3
  • 4
  • 5
  • ...
  • 8
  • Volgende pagina
Nieuw bericht

Archief > 2015 > september

  • 16-09-2015 - Sjors Scheres wint KNCV Gouden Medaille 2015
  • 14-09-2015 - Hermen Overkleeft RSC Jeremy Knowles Award 2015 Winner
  • 03-09-2015 - Arne Mast wint KNCV Van Marumpenning 2014
  • DCS News
  • About DCS
    • Agenda
    • Board
    • ALV-2022-2023
    • ALV-2021
    • ALV-2020
  • Activities
    • Catalysis Workshop
    • NCCC
    • Travel Grant
    • Netherlands Catalysis and Chemistry Award
    • DCS Award
    • N3C Award
    • DCS Mentoring program
  • News
  • DZA
    • About DZA
    • DZA Board
  • Membership
logo
  • LinkedIn

Cookies op deze website

Deze website maakt gebruik van cookies om goed te functioneren. Als je wilt aanpassen welke cookies we mogen gebruiken, kan je jouw cookie-instellingen wijzigen. Meer informatie is beschikbaar in onze privacyverklaring.

Schakel alle cookies in Alleen essentiƫle cookies

Jouw cookie-instellingen

  1. Je ontvangt strikt noodzakelijke cookies, omdat ze nodig zijn voor het juist functioneren van deze website. Deze cookies kunt u niet uitschakelen.

  2. Deze website slaat jouw voorkeuren op zodat deze bij een volgend bezoek kunnen worden toegepast.

  3. Deze website analyseert het gebruik ervan, zodat we functionaliteit daarop kunnen aanpassen en verbeteren. De gegevens zijn anoniem.

  4. Deze website analyseert je bezoek om de inhoud beter op jouw behoeften af te stemmen.

  5. Deze website maakt gebruik van externe functionaliteit, zoals Social Media deelmogelijkheden.